Dichotomy of Atom-Economical Hydrogen-Free Reductive Amidation vs Exhaustive Reductive Amination.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02821
Abstract: Rh-catalyzed one-step reductive amidation of aldehydes has been developed. The protocol does not require an external hydrogen source and employs carbon monoxide as a deoxygenative agent. The direction of the reaction can be altered simply… read more here.
Keywords: dichotomy atom; economical hydrogen; atom economical; amidation ... See more keywords
Reductive amidation of alkyl tosylates with isocyanates by a Ni/Co-dual catalytic system.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/c9cc09377j
Abstract: Reductive amidation of alkyl tosylates with isocyanates using the Ni/Co-dual catalytic system is disclosed. The method proceeds efficiently under mild conditions, giving rise to the corresponding alkyl amides. Notably, the protocol can discriminate the steric… read more here.
Keywords: alkyl; tosylates isocyanates; alkyl tosylates; amidation ... See more keywords