Reductive Aza-Pauson-Khand Reaction of Nitriles.
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DOI: 10.1021/jacs.3c01656
Abstract: γ-Lactams are valuable heterocycles in synthetic chemistry and drug development. Here, we report a reductive aza-Pauson-Khand reaction (aza-PKR) of an alkyne, a nitrile, and Co2(CO)8. A wide array of bicyclic α,β-unsaturated γ-lactams containing two adjacent… read more here.
Keywords: reductive aza; pauson khand; reaction; khand reaction ... See more keywords