Catalytic Enantioselective Carbonyl Propargylation Beyond Preformed Carbanions: Reductive Coupling and Hydrogen Auto‐Transfer
Sign Up to like & getrecommendations! Published in 2019 at "ChemCatChem"
DOI: 10.1002/cctc.201801121
Abstract: Chiral metal complexes catalyze enantioselective carbonyl propargylation via reductive coupling or as hydrogen auto‐transfer processes, in which reactant alcohols serve dually as reductant and carbonyl proelectrophile. Unlike classical propargylation protocols, which rely on allenylmetal reagents… read more here.
Keywords: carbonyl propargylation; propargylation; enantioselective carbonyl; coupling hydrogen ... See more keywords
Roughness-dependent Electro-reductive Coupling of Nitrobenzenes and Aldehydes on Copper Electrodes.
Sign Up to like & getrecommendations! Published in 2023 at "ChemSusChem"
DOI: 10.1002/cssc.202300180
Abstract: The electro-reductive coupling of nitro and carbonyl compounds enables a facile, environmentally friendly and energy benign transformation toward value-added nitrones or imines, but the selectivity is still challenging. Here, the surface roughness of Cu electrodes… read more here.
Keywords: electro reductive; roughness dependent; reductive coupling; dependent electro ... See more keywords
Green and highly efficient approach for the reductive coupling of nitroarenes to azoxyarenes using the new mesoporous Fe3O4@SiO2@Co–Zr–Sb catalyst
Sign Up to like & getrecommendations! Published in 2020 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-020-04126-7
Abstract: Efficient, green, simple and environmentally friendly approach for the straightforward reductive coupling of nitroarenes to the corresponding azoxyarenes has been developed in the presence of Fe3O4@SiO2@Co–Zr–Sb as a novel recyclable nanocatalyst. The Co–Zr–Sb trimetallic nanoparticles… read more here.
Keywords: fe3o4 sio2; coupling nitroarenes; reductive coupling; approach ... See more keywords
Mechanistic insights into asymmetric reductive coupling of isoquinolines by a chiral diboron with DFT calculations
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2018.02.001
Abstract: Abstract We report our complete mechanistic study on the highly diastereo- and enantioselective reductive coupling of isoquinoline templated by a chiral diboron. An uncommon activation mode, activation of the B-B bond via double N-B coordination… read more here.
Keywords: diboron; insights asymmetric; chiral diboron; reductive coupling ... See more keywords
Reductive coupling of diisopropylcarbodiimide by a dirhenium carbonyl complex
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2019.06.027
Abstract: Abstract The reaction of Re 2 (CO) 8 (μ-H)[μ-η 2 -C(H) = C(H)Bu n ] with N , N ′-diisopropylcarbodiimide yielded the new rhenium diamidinate complex [Re(CO) 4 ] 2 [(μ-C 2 (N{iPr}) 4 ], 2 ,… read more here.
Keywords: diisopropylcarbodiimide dirhenium; coupling diisopropylcarbodiimide; dirhenium carbonyl; ligand ... See more keywords
DFT Studies on the Mechanisms of Enantioselective Ni-Catalyzed Reductive Coupling Reactions to Form 1,1-diarylalkanes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2021.122042
Abstract: ABSTRACT The detail mechanisms of enantioselective Ni-catalyzed reductive coupling of 5-bromide-2-methoxypyridine (R1) and (1-chloropropyl) benzene (R2) to form 1,1-diarylalkanes (R, S)-P were studied using Density Functional Theory calculations. The overall catalytic cycles include the following… read more here.
Keywords: mechanisms enantioselective; form diarylalkanes; enantioselective catalyzed; reductive coupling ... See more keywords
Reductive coupling of phthalic anhydrides with aliphatic ketones by low-valent titanium: Unusual two-to-one coupling for preparation of 3,3-disubstituted phthalides
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.130820
Abstract: Abstract The reductive coupling of phthalic anhydrides with acetone by Zn-TiCl4 in THF gave two-to-one and one-to-one coupled products. The coupled products were transformed to 3,3-diisopropyl-, 3-isopropylidene-, and 3-isopropylphthalides. In addition, the reductive coupling of… read more here.
Keywords: coupling phthalic; two one; aliphatic ketones; phthalic anhydrides ... See more keywords
Cation Bridge Mediating Homo- and Cross-Coupling in Copper-Catalyzed Reductive Coupling of Benzaldehyde and Benzophenone.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c02392
Abstract: A novel mechanism of organobase-mediated Brook rearrangement and C-C coupling in the copper-catalyzed reductive coupling of benzaldehyde and benzophenone is proposed. The results demonstrate that this reaction proceeds mainly through five sequential elementary steps: transmetalation,… read more here.
Keywords: coupling copper; reductive coupling; coupling benzaldehyde; brook rearrangement ... See more keywords
Ni-Catalyzed Reductive Coupling of Alkynes and Amides to Access Multi-Functionalized Indoles.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03971
Abstract: A nickel-catalyzed reductive coupling of alkynes and amides, followed by base-free transmetalation, proceeded selectively in the presence of an uncommon bidentate primary aminophosphine ligand to access highly functionalized indoles comprising biologically important trifluoromethyl groups and… read more here.
Keywords: functionalized indoles; alkynes amides; reductive coupling; catalyzed reductive ... See more keywords
Nickel-Catalyzed Reductive Coupling of γ-Metalated Ketones with Unactivated Alkyl Bromides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01390
Abstract: A nickel-catalyzed reductive cross-coupling reaction of aryl cyclopropyl ketones with easily accessible unactivated alkyl bromides to access aryl alkyl ketones has been developed. This strategy facilitates access to various of γ-alkyl-substituted ketones via ring opening… read more here.
Keywords: unactivated alkyl; nickel catalyzed; reductive coupling; alkyl bromides ... See more keywords
Ni-Catalyzed Reductive Coupling of Heteroaryl Bromides with Tertiary Alkyl Halides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03598
Abstract: We disclose here a nickel-catalyzed reductive coupling of bromopyridines with tertiary alkyl bromides for the synthesis of alkylated pyridines bearing an all-carbon quaternary center. This strategy features mild conditions, broad substrate scope, and high functional… read more here.
Keywords: coupling heteroaryl; tertiary alkyl; reductive coupling; heteroaryl bromides ... See more keywords