Deaminative Reductive Methylation of Alkylpyridinium Salts.
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DOI: 10.1021/acs.orglett.1c02458
Abstract: Methyl groups can imbue valuable properties in organic molecules, often leading to enhanced bioactivity. To enable efficient installation of methyl groups on simple building blocks and in late-stage functionalization, a nickel-catalyzed reductive coupling of secondary… read more here.
Keywords: alkylpyridinium; alkylpyridinium salts; reductive methylation; deaminative reductive ... See more keywords