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1
Published in 2019 at "Nature Cell Biology"
DOI: 10.1038/s41556-018-0196-y
Abstract: Epithelial–mesenchymal transition (EMT) is a crucial embryonic programme that is executed by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and other diseases. However, the causal role of EMT and EMT-TFs in…
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Keywords:
non redundant;
emt transcription;
emt tfs;
redundant functions ... See more keywords
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1
Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41116-1
Abstract: Adhesion signaling between epithelial cells and the extracellular matrix plays a critical role in maintaining tissue homeostasis and the response to tissue damage. Focal adhesion kinase (FAK) and its close relative Pyk2 are non-receptor tyrosine…
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Keywords:
non redundant;
epithelial repair;
redundant functions;
colitis ... See more keywords
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1
Published in 2022 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14808
Abstract: The integrity and functions of epithelial barriers depend on the formation of adherens junctions (AJs) and tight junctions (TJs). A characteristic feature of AJs and TJs is their association with the cortical cytoskeleton composed of…
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Keywords:
actin isoforms;
redundant functions;
myosin;
unique redundant ... See more keywords
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0
Published in 2021 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-21-0601
Abstract: Cancer-associated fibroblast (CAF) heterogeneity is increasingly appreciated, but the origins and functions of distinct CAF subtypes remain poorly understood. The abundant and transcriptionally diverse CAF population in pancreatic ductal adenocarcinoma (PDAC) is thought to arise…
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Keywords:
non redundant;
cancer associated;
redundant functions;
cancer ... See more keywords