Multidimensional reference regions is a new tool to optimize the personalized care of patients
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DOI: 10.1038/s41598-025-10173-0
Abstract: Medical diagnostic processes often rely on comprehensive biological assessments, but current methods have drawbacks, such as insufficient consideration of variable dependence. Modern databases enable precise estimation of multidimensional variable distributions, prompting this study to enhance… read more here.
Keywords: methodology; reference; multidimensional reference; regions new ... See more keywords
Rectangular multivariate normal prediction regions for setting reference regions in laboratory medicine
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biopharmaceutical Statistics"
DOI: 10.1080/10543406.2022.2105347
Abstract: ABSTRACT Reference intervals are among the most widely used medical decision-making tools and are invaluable in the interpretation of laboratory results of patients. Moreover, when multiple biochemical analytes are measured on each patient, a multivariate… read more here.
Keywords: reference intervals; reference regions; reference; prediction ... See more keywords
Reference ranges: Why tolerance intervals should not be used. Comment on Liu, Bretz and Cortina-Borja, Reference range: Which statistical intervals to use? SMMR, 2021,Vol. 30(2) 523–534
Sign Up to like & getrecommendations! Published in 2022 at "Statistical Methods in Medical Research"
DOI: 10.1177/09622802221114538
Abstract: In their recent position paper on establishing reference regions for quantitative markers for use in medical diagnostics, Liu et al. 1 made a case for considering tolerance region estimation as the appropriate statistical tool for… read more here.
Keywords: reference regions; reference; tolerance; distribution ... See more keywords
An update of IPCC climate reference regions for subcontinental analysis of climate model data: definition and aggregated datasets
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DOI: 10.5194/essd-12-2959-2020
Abstract: Abstract. Several sets of reference regions have been proposed in the literature for the regional synthesis of observed and model-projected climate change information. A popular example is the set of reference regions introduced in the… read more here.
Keywords: reference regions; climate; aggregated datasets; climate model ... See more keywords