Articles with "refractoriness" as a keyword



Is there a role for the international prognostic index in follicular lymphoma?

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Published in 2017 at "Annals of Hematology"

DOI: 10.1007/s00277-017-3197-1

Abstract: Dear Editor, Although FL is generally considered an indolent disorder, in the last few years, it has come to light that a subset of patients ( 1 5 – 2 0% ) w i t… read more here.

Keywords: risk; high risk; study; risk flipi ... See more keywords

CRAFITY score as a predictive marker for refractoriness to atezolizumab plus bevacizumab therapy in hepatocellular carcinoma: a multicenter retrospective study

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Published in 2024 at "Journal of Gastroenterology"

DOI: 10.1007/s00535-024-02150-7

Abstract: Although atezolizumab plus bevacizumab (Atezo/Bev) therapy has been used as the preferred first-line treatment for advanced hepatocellular carcinoma (HCC), up to 26% of patients do not achieve disease control, suggesting alternative treatments might be more… read more here.

Keywords: therapy; refractoriness; line; atezolizumab plus ... See more keywords

Impact of daratumumab refractoriness on clinical outcomes following CAR T-cell therapy for relapsed refractory multiple myeloma

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Published in 2025 at "Blood Cancer Journal"

DOI: 10.1038/s41408-025-01343-4

Abstract: Dear Editor,Patients with relapsed refractory multiple myeloma (RRMM) having progressed after three prior lines of therapy including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 monoclonal antibody, have a dismal prognosis, with a median… read more here.

Keywords: prior lines; therapy; car cell; cell ... See more keywords

P302 Serum IL-6 is associated with treatment refractoriness in acute severe ulcerative colitis

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Published in 2021 at "Journal of Crohn's and Colitis"

DOI: 10.1093/ecco-jcc/jjab076.426

Abstract: Response to therapy in acute severe ulcerative colitis (ASUC) is highly variable ranging from steroid response to salvage therapy failure and emergency colectomy. Biomarkers that accurately predict outcomes in ASUC early in the admission may… read more here.

Keywords: serum; treatment; patients asuc; responders ifx ... See more keywords

A Sequential Cohort Study of Pathogen Reduced Platelet Component Transfusion without Use of Leukocyte Reduction for Hematopoietic Stem Cell Transplant (HSCT): Impact on Clinical Refractoriness

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Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-112305

Abstract: Introduction: HSCT patients require platelet components (PC) for support of thrombocytopenia. Donors are tested for selected viruses to prevent transfusion-transmission infection (TTI), and PC are screened for bacteria and irradiated to prevent transfusion associated graft… read more here.

Keywords: study; clinical refractoriness; transfusion; refractoriness ... See more keywords

A unified clinical algorithm for the diagnosis and management of platelet transfusion refractoriness: A systematic synthesis and proposed framework

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Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-6693

Abstract: Background: Platelet transfusion refractoriness (PTR), or inability to achieve an acceptable rise in platelet count following transfusion, is found in up to 30% of heavily transfused patients and is associated with increased bleeding, increased length… read more here.

Keywords: clinical algorithm; platelet; refractoriness; management ... See more keywords

Association of Peri-ictal MRI Abnormalities With Mortality, Antiseizure Medication Refractoriness, and Morbidity in Status Epilepticus

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Published in 2022 at "Neurology"

DOI: 10.1212/wnl.0000000000201599

Abstract: Background and Objectives Status epilepticus (SE) is a life-threatening emergency requiring a prompt assessment of patient prognosis to guide management. MRI allows the identification of peri-ictal MRI abnormalities (PMAs) and provides insight into brain structural… read more here.

Keywords: pma; status epilepticus; mortality; mri ... See more keywords

Plasma arginase-1 as a predictive marker for early transarterial chemoembolization refractoriness in unresectable hepatocellular carcinoma

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.1014653

Abstract: Objective To explore the relationship between plasma arginase-1 (ARG1) and early transarterial chemoembolization (TACE) refractoriness in patients with hepatocellular carcinoma (HCC) and develop nomograms for predicting early TACE refractoriness. Methods A total of 200 patients… read more here.

Keywords: early tace; tace; plasma arginase; tace refractoriness ... See more keywords

Systemic and Peripheral Mechanisms of Cortical Stimulation-Induced Analgesia and Refractoriness in a Rat Model of Neuropathic Pain

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24097796

Abstract: Epidural motor cortex stimulation (MCS) is an effective treatment for refractory neuropathic pain; however, some individuals are unresponsive. In this study, we correlated the effectiveness of MCS and refractoriness with the expression of cytokines, neurotrophins,… read more here.

Keywords: nerve; mcs; neuropathic pain; stimulation ... See more keywords

Multiple ASM Administration via Percutaneous Feeding Tube as a Cause of Pseudo-Refractoriness Leading to Recurrent Seizure Clusters.

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Published in 2024 at "Neurology India"

DOI: 10.4103/neurol-india.ni_1146_22

Abstract: It is important to identify true refractoriness of seizures, before escalation of anti-seizure medications, to avoid side effects of medications. Bioavailability of medications changes with the formulations used and changes significantly with the route of… read more here.

Keywords: asm administration; via percutaneous; seizure; refractoriness ... See more keywords