Effectiveness of ketogenic diet in treatment of patients with refractory chronic migraine
Sign Up to like & getrecommendations! Published in 2021 at "Neurological Sciences"
DOI: 10.1007/s10072-021-05078-5
Abstract: Ketogenic diet (KD) is based on restriction of carbohydrate intake. Metabolism is forced to obtain energy starting from β-oxidation of fatty acids which, turned into ketone bodies, can also be used by central nervous system… read more here.
Keywords: migraine; treatment; patients refractory; chronic migraine ... See more keywords
Topical Therapies for Refractory Chronic Rhinosinusitis.
Sign Up to like & getrecommendations! Published in 2017 at "Otolaryngologic clinics of North America"
DOI: 10.1016/j.otc.2016.08.011
Abstract: Topical therapy has become an important tool in the otolaryngologist's armamentarium for refractory chronic rhinosinusitis (CRS). Daily high-volume sinonasal saline irrigation and standard metered-dose topical nasal steroid therapy are supported by the most evidence. Nonstandard… read more here.
Keywords: chronic rhinosinusitis; topical therapies; therapies refractory; therapy ... See more keywords
Third-generation anti-CD19 CAR T cells for relapsed/refractory chronic lymphocytic leukemia: a phase 1/2 study
Sign Up to like & getrecommendations! Published in 2024 at "Leukemia"
DOI: 10.1038/s41375-024-02392-7
Abstract: Third-generation chimeric antigen receptor T cells (CARTs) for relapsed or refractory (r/r) chronic lymphocytic leukemia (CLL) may improve efficacy compared to second-generation CARTs due to their enhanced CAR design. We performed the first phase 1/2… read more here.
Keywords: generation; third generation; chronic lymphocytic; refractory chronic ... See more keywords
Pharmacotherapy of relapsed/refractory chronic lymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2017.1324420
Abstract: ABSTRACT Introduction: The treatment of relapsed/refractory (RR) CLL has been revolutionized by the advent of the new oral inhibitors of B-cell receptor (BCR) signaling and the pro-survival protein, B-cell lymphoma 2 (BCL2). Additionally, new and… read more here.
Keywords: relapsed refractory; lymphocytic leukemia; pharmacotherapy relapsed; pharmacotherapy ... See more keywords
Initial Success: Camlipixant in Refractory Chronic Cough
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.202503-0651le
Abstract: at Day 28, compared with baseline. This improvement was signi fi cantly greater than the ef fi cacy observed in the group that was treated with 12.5 mg twice a day ( P =0.0976, not… read more here.
Keywords: camlipixant refractory; chronic cough; refractory chronic; success camlipixant ... See more keywords
Clinical predictors of therapeutic failure of occipital nerve stimulation in refractory chronic cluster headache
Sign Up to like & getrecommendations! Published in 2024 at "Cephalalgia"
DOI: 10.1177/03331024241254078
Abstract: Background Occipital nerve stimulation (ONS) is a treatment with evidence in refractory chronic cluster headache (CCH). However, the variable response rate and cost make it necessary to investigate predictors of response. Methods This is a… read more here.
Keywords: nerve stimulation; response; occipital nerve; refractory chronic ... See more keywords
Antitussive efficacy of the current treatment protocol for refractory chronic cough: our real-world experience in a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/17534666231167716
Abstract: Background: The management of refractory chronic cough (RCC) is a great challenge. Neuromodulators have long been used for RCC with imperfect efficacy. Objectives: We summarized the outcomes of the current treatments used at our specialist… read more here.
Keywords: refractory chronic; chronic cough; rcc; cough ... See more keywords
An open-label study of the tolerability and potential efficacy of memantine for treating refractory chronic cough
Sign Up to like & getrecommendations! Published in 2021 at "ERJ Open Research"
DOI: 10.1183/23120541.00447-2021
Abstract: Refractory chronic cough (RCC) is defined as cough lasting longer than 8 weeks either in the absence of an identifiable underlying cause or that remains resistant to treating any potential underlying causes [1]. Affected patients have… read more here.
Keywords: cough; open label; label study; chronic cough ... See more keywords
A double-blind randomised placebo-controlled trial investigating the effects of lesogaberan on the objective cough frequency and capsaicin-evoked coughs in patients with refractory chronic cough
Sign Up to like & getrecommendations! Published in 2022 at "ERJ Open Research"
DOI: 10.1183/23120541.00546-2021
Abstract: Objective Baclofen is a centrally acting γ-aminobutyric acid type B (GABAB) receptor agonist which reduces gastro-oesophageal reflux and suppresses the cough reflex; however, central nervous system side-effects limit its use. Lesogaberan is a novel peripherally… read more here.
Keywords: refractory chronic; cough frequency; chronic cough; cough ... See more keywords
Repeat expansions in RFC1 gene in refractory chronic cough
Sign Up to like & getrecommendations! Published in 2024 at "ERJ Open Research"
DOI: 10.1183/23120541.00584-2024
Abstract: Introduction Refractory chronic cough (RCC), persisting despite addressing contributory diagnoses, is likely underpinned by neurally mediated cough hypersensitivity. RFC1 disorders are genetic neurodegenerative conditions caused by biallelic RFC1 repeat expansion sequences, commonly presenting with cough,… read more here.
Keywords: chronic cough; refractory chronic; rfc1; repeat expansions ... See more keywords
Correlation analysis of TGF-β1, MMP-9, TIMP-1, IL-1, IL-4, IL-6, IL-17, and TNF-α in refractory chronic rhinosinusitis: A retrospective study.
Sign Up to like & getrecommendations! Published in 2022 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v50i4.527
Abstract: OBJECTIVE To investigate the potential correlation of transforming growth factor-β (TGF-β), matrix metalloprotein 9 (MMP-9), tissue inhibitor of metalloproteinases 1 (TIMP-1), Interleukin 1 (IL-1), IL-4, IL-6, IL-17, and tumor necrosis factor alpha (TNF-α) in refractory… read more here.
Keywords: refractory chronic; group; mmp timp; chronic rhinosinusitis ... See more keywords