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Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.01482-2018
Abstract: Sarcoidosis is a systemic disorder of unknown aetiology characterised by the formation of non-caseating epithelioid granulomas in involved organs. Although a spontaneous remission is frequent, up to 28–53% of patients may follow a persistent active…
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Keywords:
dramatic response;
response refractory;
ruxolitinib patient;
refractory sarcoidosis ... See more keywords
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Published in 2022 at "Respiratory Research"
DOI: 10.1186/s12931-022-01971-5
Abstract: Background Infliximab is a monoclonal antibody that binds and neutralizes circulating tumor necrosis factor-alpha, a key inflammatory cytokine in the pathophysiology of sarcoidosis. Despite the paucity of randomized clinical trials, infliximab is often considered a…
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Keywords:
infliximab;
treatment;
sarcoidosis;
therapy refractory ... See more keywords