Rechallenge clozapine after agranulocytosis in refractory schizophrenia. A case report
Sign Up to like & getrecommendations! Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2017.01.1411
Abstract: Introduction Clozapine, is widely prescribed for treatment of refractory schizophrenia, but its use may be limited by potentially serious adverse effects. The most feared complication remains agranulocytosis [absolute neutrophil count (ANC) Objectives To know procedures… read more here.
Keywords: schizophrenia; rechallenge; refractory schizophrenia; agranulocytosis refractory ... See more keywords
Generation of refractory schizophrenia patient-derived induced pluripotent stem cell line UJSi001-A.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101460
Abstract: Schizophrenia is considered one of the most serious mental disorders nowadays. Approximately 30-60% of people with schizophrenia do not present adequate response to drug treatment and persist with symptoms of the disease; they are known… read more here.
Keywords: schizophrenia; pluripotent stem; schizophrenia patient; induced pluripotent ... See more keywords
Combination of strategies to initiate clozapine for refractory schizophrenia in a patient with low neutrophil levels
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-247734
Abstract: Clozapine is the only drug with confirmed efficacy for refractory schizophrenia; however, its use is restricted due to the risk of potentially life-threatening side effects, such as agranulocytosis. Although this restriction ensures safety against haematological… read more here.
Keywords: refractory schizophrenia; neutrophil levels; low neutrophil;