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   Articles with "reg3a" as a keyword



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MicroRNA-10a-3p mediates Th17/Treg cell balance and improves renal injury by inhibiting REG3A in lupus nephritis.

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recommendations! Published in 2020 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2020.106891

Abstract: BACKGROUND The therapeutic approaches guided toward microRNAs (miRNAs) have been extensively explored in lupus nephritis (LN), but the precise position of miR-10a-3p posted in disease is not translated thoroughly. Therein, this work pivoting on miR-10a-3p… read more here.

Keywords: th17 treg; reg3a; renal injury; mir 10a ... See more keywords
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LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription

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recommendations! Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-13313-z

Abstract: Protein products of the regenerating islet-derived (REG) gene family are important regulators of many cellular processes. Here we functionally characterise a non-protein coding product of the family, the long noncoding RNA (lncRNA) REG1CP that is… read more here.

Keywords: reg3a transcription; reg1cp promotes; reg3a; family ... See more keywords
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High incidence of extensive chronic graft-versus-host disease in patients with the REG3A rs7588571 non-GG genotype

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0185213

Abstract: Regenerating islet-derived protein 3 alpha (REG3A) is a biomarker of lower gastrointestinal graft-versus-host disease (GVHD); however, the biological role of REG3A in the pathophysiology of GVHD is not understood. Here, we examined the association between… read more here.

Keywords: incidence; rs7588571 non; non genotype; reg3a ... See more keywords
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REG3A overexpression functions as a negative predictive and prognostic biomarker in rectal cancer patients receiving CCRT.

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recommendations! Published in 2023 at "Histology and histopathology"

DOI: 10.14670/hh-18-615

Abstract: BACKGROUND Concurrent chemoradiotherapy (CCRT) is suggested before resection surgery in the control of rectal cancer. Unfortunately, treatment outcomes are widely variable and highly patient-specific. Notably, rectal cancer patients with distant metastasis generally have a much… read more here.

Keywords: reg3a overexpression; cancer patients; reg3a; rectal cancer ... See more keywords