Regenerating islet-derived protein 3-α is a prognostic biomarker for gastrointestinal chronic graft-versus-host disease
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021005420
Abstract: Key Points Plasma levels of Reg3α were significantly increased in patients with GI-cGVHD compared with those without GI-cGVHD in 2 independent cohorts. Reg3α is a prognostic biomarker that identifies the likelihood of NRM in patients… read more here.
Keywords: biomarker; derived protein; prognostic biomarker; regenerating islet ... See more keywords
Four Decades After the Discovery of Regenerating Islet-Derived (Reg) Proteins: Current Understanding and Challenges
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2019.00235
Abstract: Regenerating islet-derived (Reg) proteins have emerged as multifunctional agents with pro-proliferative, anti-apoptotic, differentiation-inducing and bactericidal properties. Over the last 40 years since first discovered, Reg proteins have been implicated in a gamut of maladies including… read more here.
Keywords: reg proteins; islet derived; regenerating islet; biology ... See more keywords
Role of Regenerating Islet-Derived Protein 3A in Gastrointestinal Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.01449
Abstract: Regenerating islet-derived protein 3A (Reg3A), a protein mainly expressed in the digestive system, has been found over-expressed in many kinds of gastrointestinal cancer, including hepatocellular carcinoma, pancreatic cancer, gastric cancer, and colorectal cancer, therefore has… read more here.
Keywords: derived protein; islet derived; gastrointestinal cancer; regenerating islet ... See more keywords
Role of regenerating islet-derived proteins in inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2020 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v26.i21.2702
Abstract: Inflammatory bowel disease (IBD) is an inflammatory disorder of the gastrointestinal tract that affects millions of patients worldwide. It has a complex and multifactorial etiology leading to excessive exposure of intestinal epithelium to microbial antigens,… read more here.
Keywords: bowel disease; inflammatory bowel; islet derived; disease ... See more keywords