Circular bivalent aptamers enhance the activation of the regenerative signaling pathway for repairing liver injury in vivo.
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DOI: 10.1039/d2cc06176g
Abstract: We developed a circular bivalent aptamer (CBA) to precisely activate membrane receptor-mediated regenerative signaling for liver repair in vivo. The CBA showed enhanced biostability and receptor binding avidity, achieving effective pathway activation and satisfactory treatment… read more here.
Keywords: regenerative signaling; circular bivalent; liver injury; pathway ... See more keywords