Mesenchymal stromal cell‐derived extracellular vesicles for regenerative therapy and immune modulation: Progress and challenges toward clinical application
Sign Up to like & getrecommendations! Published in 2019 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0114
Abstract: Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) have emerged as a promising form of regenerative therapy and immune modulation. Fundamental advances in our understanding of MSCs and EVs have allowed these fields to… read more here.
Keywords: extracellular vesicles; mesenchymal stromal; regenerative therapy; therapy ... See more keywords
[Strategies for a regenerative therapy of hearing loss. German version].
Sign Up to like & getrecommendations! Published in 2018 at "HNO"
DOI: 10.1007/s00106-017-0466-1
Abstract: Despite impressive technical progress in the field of conventional hearing aids and implantable hearing systems, the hopes for the treatment of inner ear diseases such as hearing loss and tinnitus have become increasingly directed toward… read more here.
Keywords: strategies regenerative; hearing loss; inner ear; regenerative therapy ... See more keywords
Translational challenges in advancing regenerative therapy for treating neurological disorders using nanotechnology.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2019.05.003
Abstract: The focus of regenerative therapies is to replace or enrich diseased or injured cells and tissue in an attempt to replenish the local environment and function, while slowing or halting further degeneration. Targeting neurological diseases… read more here.
Keywords: translational challenges; regenerative therapy; advancing regenerative; nanotechnology ... See more keywords
Regenerative therapy by using mesenchymal stem cells-derived exosomes in COVID-19 treatment. The potential role and underlying mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2022.03.006
Abstract: COVID-19 disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), started in December 2019 in Wuhan, China, and quickly became the global pandemic. The high spread rate, relatively high mortality rate, and the… read more here.
Keywords: treatment; stem cells; regenerative therapy; role ... See more keywords
Scalable manufacturing of clinical‐grade differentiated cardiomyocytes derived from human‐induced pluripotent stem cells for regenerative therapy
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13248
Abstract: Basic research on human pluripotent stem cell (hPSC)‐derived cardiomyocytes (CMs) for cardiac regenerative therapy is one of the most active and complex fields to achieve this alternative to heart transplantation and requires the integration of… read more here.
Keywords: regenerative therapy; heart; therapy; pluripotent stem ... See more keywords
Reconstructive and Regenerative Therapy of Atrophic Jaws with New Implant Techniques: Preclinical and Clinical Studies
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/8252383
Abstract: Nowadays, dental implants represent a reliable and successful procedure for the prosthetic restoration of partially and totally edentulous patients, with high survival and success rates in the short, medium, and long term. However, a sufficient… read more here.
Keywords: bone regeneration; regenerative therapy; reconstructive regenerative; regeneration ... See more keywords
Metabolic Glycoengineering: A Promising Strategy to Remodel Microenvironments for Regenerative Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Stem Cells International"
DOI: 10.1155/2023/1655750
Abstract: Cell-based regenerative therapy utilizes the differentiation potential of stem cells to rejuvenate tissues. But the dynamic fate of stem cells is calling for precise control to optimize their therapeutic efficiency. Stem cell fate is regulated… read more here.
Keywords: cell; regenerative therapy; stem cells; metabolic glycoengineering ... See more keywords
A Biomimetic Smart Nanoplatform as “Inflammation Scavenger” for Regenerative Therapy of Periodontal Tissue
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s384481
Abstract: Introduction The functional reconstruction of periodontal tissue defects remains a clinical challenge due to excessive and prolonged host response to various endogenous and exogenous pro-inflammatory stimuli. Thus, a biomimetic nanoplatform with the capability of modulating… read more here.
Keywords: therapy periodontal; inflammation scavenger; regenerative therapy; nanoplatform ... See more keywords
Plant-Derived Exosome-like Nanoparticles for Biomedical Applications and Regenerative Therapy
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DOI: 10.3390/biomedicines11041053
Abstract: Plant-derived exosome-like nanoparticles (PDENs) comprise various bioactive biomolecules. As an alternative cell-free therapeutic approach, they have the potential to deliver nano-bioactive compounds to the human body, and thus lead to various anti-inflammatory, antioxidant, and anti-tumor… read more here.
Keywords: derived exosome; regenerative therapy; exosome like; plant derived ... See more keywords
Neurotrophic Factors as Regenerative Therapy for Neurodegenerative Diseases: Current Status, Challenges and Future Perspectives
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043866
Abstract: Neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), multiple sclerosis (MS), spinal cord injury (SCI), and amyotrophic lateral sclerosis (ALS), are characterized by acute or chronic progressive loss of one or… read more here.
Keywords: neurotrophic factors; regenerative therapy; challenges future; therapy neurodegenerative ... See more keywords
Potential Role for Stem Cell Regenerative Therapy as a Treatment for Degenerative Disc Disease and Low Back Pain: A Systematic Review
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108893
Abstract: Back pain is the single leading cause of disability worldwide. Despite the prevalence and morbidity of lower back pain, we still lack a gold-standard treatment that restores the physiological function of degenerated intervertebral discs. Recently,… read more here.
Keywords: treatment; regenerative therapy; back pain; stem cell ... See more keywords