Synthesis, characterization, in vitro DNA photocleavage and cytotoxicity studies of 4-arylazo-1-phenyl-3-(2-thienyl)-5-hydroxy-5-trifluoromethylpyrazolines and regioisomeric 4-arylazo-1-phenyl-5(3)-(2-thienyl)-3(5)-trifluoromethylpyrazoles
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2020.109573
Abstract: Abstract 1-(2-Thienyl)-2-arylazo-4,4,4-trifluorobutane-1,3-diones (4), generated by the condensation of aryldiazonium salts (2) with 4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione (3), were used as common intermediates to synthesize regioisomeric 4-arylazo-1-phenyl-5(3)-(2-thienyl)-3(5)-trifluoromethylpyrazoles (5 and 6) and 4-arylazo-1-phenyl-3-(2-thienyl)-5-hydroxy-5-trifluoromethylpyrazolines (7) by reacting with phenylhydrazine in neutral… read more here.
Keywords: regioisomeric arylazo; dna; thienyl; arylazo phenyl ... See more keywords