Characterization of iPSCs derived from low grade gliomas revealed early regional chromosomal amplifications during gliomagenesis
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DOI: 10.1007/s11060-018-03047-1
Abstract: IntroductionIDH1 mutation has been identified as an early genetic event driving low grade gliomas (LGGs) and it has been proven to exerts a powerful epigenetic effect. Cells containing IDH1 mutation are refractory to epigenetical reprogramming… read more here.
Keywords: ipsc clones; regional chromosomal; idh1 mutation; grade gliomas ... See more keywords