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Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12030242
Abstract: Sufficient colonic absorption is necessary for all systemically acting drugs in dosage forms that release the drug in the large intestine. Preclinically, colonic absorption is often investigated using the rat single-pass intestinal perfusion model. This…
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Keywords:
permeation enhancers;
regional intestinal;
drug permeability;
permeability ... See more keywords
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1
Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13020272
Abstract: The gastrointestinal tract (GIT) can be broadly divided into several regions: the stomach, the small intestine (which is subdivided to duodenum, jejunum, and ileum), and the colon. The conditions and environment in each of these…
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Keywords:
absorption;
drug absorption;
regional intestinal;
absorption biopharmaceutics ... See more keywords