A robust method to estimate regional polygenic correlation under misspecified linkage disequilibrium structure
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DOI: 10.1002/gepi.22149
Abstract: Complex traits can share a substantial proportion of their polygenic heritability. However, genome‐wide polygenic correlations between pairs of traits can mask heterogeneity in their shared polygenic effects across loci. We propose a novel method (weighted… read more here.
Keywords: polygenic correlation; regional polygenic; method; correlation ... See more keywords