Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits.
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DOI: 10.1371/journal.pcbi.1009483
Abstract: The number of variants that have a non-zero effect on a trait (i.e. polygenicity) is a fundamental parameter in the study of the genetic architecture of a complex trait. Although many previous studies have investigated… read more here.
Keywords: causal snps; architecture complex; regional polygenicity; genetic architecture ... See more keywords