Articles with "regions human" as a keyword



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Pluripotency markers in tissue and cultivated cells in vitro of different regions of human amniotic epithelium.

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Published in 2019 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2018.12.007

Abstract: Studies have described the presence of pluripotent markers in vivo and in vitro in human amnion. However, the amnion can be divided into reflected, placental and umbilical regions that are anatomically and functionally heterogeneous. Here,… read more here.

Keywords: regions human; different regions; pluripotency; amnion ... See more keywords
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Deep Phosphoproteome Landscape of Interhemispheric Functionality of Neuroanatomical Regions of the Human Brain.

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Published in 2022 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.2c00244

Abstract: Post-translational modifications (PTMs) are one of the compulsive and predominant biological processes that regulate the diverse molecular mechanism, modulate the onset of disease, and are the reason behind the functional diversity of proteins. Despite the… read more here.

Keywords: brain; neuroanatomical regions; phosphoproteome; human brain ... See more keywords
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Disparate Regions of the Human Chemokine CXCL10 Exhibit Broad-Spectrum Antimicrobial Activity against Biodefense and Antibiotic-Resistant Bacterial Pathogens

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Published in 2022 at "ACS Infectious Diseases"

DOI: 10.1021/acsinfecdis.2c00456

Abstract: CXCL10 is a pro-inflammatory chemokine produced by the host in response to microbial infection. In addition to canonical, receptor-dependent actions affecting immune-cell migration and activation, CXCL10 has also been found to directly kill a broad… read more here.

Keywords: antimicrobial activity; human chemokine; activity; antibiotic resistant ... See more keywords
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Spatial Proteomics Analysis of Soft and Stiff Regions in Human Acute Arterial Thrombus

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Published in 2023 at "Stroke"

DOI: 10.1161/strokeaha.123.042486

Abstract: Background: The soft regions of a thrombus tend to be more susceptible to r-tPA (recombinant tissue-type plasminogen activator)-mediated thrombolysis and are more easily removed by mechanical thrombectomy than the stiff counterpart. This study aimed to… read more here.

Keywords: ontology; thrombi; soft stiff; soft regions ... See more keywords
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An integrative approach to predicting the functional effects of small indels in non-coding regions of the human genome

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Published in 2017 at "BMC Bioinformatics"

DOI: 10.1186/s12859-017-1862-y

Abstract: BackgroundSmall insertions and deletions (indels) have a significant influence in human disease and, in terms of frequency, they are second only to single nucleotide variants as pathogenic mutations. As the majority of mutations associated with… read more here.

Keywords: regions human; coding regions; human genome; indels non ... See more keywords
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Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states

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Published in 2019 at "eLife"

DOI: 10.7554/elife.50259

Abstract: Small heat shock proteins (sHSPs) are nature’s ‘first responders’ to cellular stress, interacting with affected proteins to prevent their aggregation. Little is known about sHSP structure beyond its structured α-crystallin domain (ACD), which is flanked… read more here.

Keywords: heat shock; regions human; ensemble quasi; small heat ... See more keywords