Tandem repeats in giant archaeal Borg elements undergo rapid evolution and create new intrinsically disordered regions in proteins
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DOI: 10.1371/journal.pbio.3001980
Abstract: Borgs are huge, linear extrachromosomal elements associated with anaerobic methane-oxidizing archaea. Striking features of Borg genomes are pervasive tandem direct repeat (TR) regions. Here, we present six new Borg genomes and investigate the characteristics of… read more here.
Keywords: intrinsically disordered; disordered regions; regions proteins; borg ... See more keywords
Characterization of intrinsically disordered regions in proteins informed by human genetic diversity
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1009911
Abstract: All proteomes contain both proteins and polypeptide segments that don’t form a defined three-dimensional structure yet are biologically active—called intrinsically disordered proteins and regions (IDPs and IDRs). Most of these IDPs/IDRs lack useful functional annotation… read more here.
Keywords: intrinsically disordered; characterization intrinsically; disordered regions; regions proteins ... See more keywords