Ni-Catalyzed Regioselective Alkylarylation of Vinylarenes via C(sp3)-C(sp3)/C(sp3)-C(sp2) Bond Formation and Mechanistic Studies.
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DOI: 10.1021/jacs.8b05374
Abstract: We report a Ni-catalyzed regioselective alkylarylation of vinylarenes with alkyl halides and arylzinc reagents to generate 1,1-diarylalkanes. The reaction proceeds well with primary, secondary and tertiary alkyl halides, and electronically diverse arylzinc reagents. Mechanistic investigations… read more here.
Keywords: sp3; regioselective alkylarylation; alkylarylation vinylarenes; catalyzed regioselective ... See more keywords