Value-added carbohydrate building blocks by regioselective O-alkylation of C-glucosyl compounds.
Sign Up to like & getrecommendations! Published in 2019 at "Carbohydrate research"
DOI: 10.1016/j.carres.2019.03.008
Abstract: Functionalized carbohydrates and especially functionalized C-glycosides are useful intermediates for the synthesis of complex carbohydrates of interest. In this paper, we describe the synthesis of C-azidopropylglucopyranosides and give a full account of their regioselective acylation… read more here.
Keywords: alkylation glucosyl; regioselective alkylation; glucosyl compounds; carbohydrate ... See more keywords
Regioselective alkylation reaction of the 2′-deoxyctidine with 9-aminomethyl derivatives of SN38
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.08.096
Abstract: Abstract We present first evidence of a spontaneous alkylation of the 2′-deoxycytidine by potential topoisomerase I inhibitors from camptothecins family. The 7-ethyl-9-(N-morpholino)methyl-10-hydroxycamptothecin and the 7-ethyl-9-(N-pyrrolidinyl)methyl-10-hydoxycamptothecin regioselectively alkylate spontaneously an exo-cyclic nitrogen (N4) of the 2′-… read more here.
Keywords: regioselective alkylation; alkylation; alkylation reaction; reaction ... See more keywords
Regioselective N–alkylation of 2– (3,4–dimethoxyphenyl)imidazo[4,5–b] and [4,5–c]pyridine oxide derivatives : Synthesis and structure elucidation by NMR
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.07.058
Abstract: Abstract Imidazopyridines can exist in several tautomeric forms such as benzimidazole or purine condensed systems. Regioselectivities were determined for N-alkylations of 2-(3,4-dimethoxyphenyl)- imidazopyridines and their 4 and 5-oxides (2–4, 13, 14) with n-butyl and 4-fluorobenzyl… read more here.
Keywords: imidazo pyridine; regioselective alkylation; pyridine oxide; structure ... See more keywords
Coordination effect enabled palladium-catalyzed regioselective O-alkylation of 2-pyridones.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06110k
Abstract: A novel tactic for the regioselective O-alkylation of 2-pyridones has been realized through palladium catalysis in moderate to high yields. The coordination effect between palladium and nitrogen on the pyridine ring plays a versatile role. read more here.
Keywords: regioselective alkylation; coordination effect; alkylation pyridones; palladium ... See more keywords
Regioselective O-alkylation of 2-pyridones by TfOH-catalyzed carbenoid insertion.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc05676c
Abstract: Selective alkylation of 2-pyridone could solve a challenge in chemistry and streamline the synthesis of important molecules. Here we report the regioselective O-alkylation of 2-pyridones by TfOH-catalyzed carbenoid insertion. In the catalytic system, alkylation of… read more here.
Keywords: catalyzed carbenoid; tfoh catalyzed; alkylation pyridones; alkylation ... See more keywords