Nickel-Catalyzed Chemo- and Regioselective Arylcyanation of β,γ-Unsaturated Amides.
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DOI: 10.1021/acs.orglett.2c01360
Abstract: A nickel-catalyzed intermolecular arylcyanation of 8-aminoquinolinyl β,γ-unsaturated amides is reported. The three-component reaction directly afforded diverse β-cyano γ-aryl amides with exclusive chemo- and regioselectivity. The synthetic practicality of this approach is further demonstrated through multigram… read more here.
Keywords: catalyzed chemo; nickel catalyzed; regioselective arylcyanation; unsaturated amides ... See more keywords