Regioselective Transformation of the Cyano Group of Triterpene α,β-Alkenenitriles
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DOI: 10.1007/s10600-017-2091-3
Abstract: Unsaturated acids, including difficultly accessible ceanothane-type ones, were prepared via alkaline hydrolysis of semi-synthetic triterpenoids with 1-cyano- or 3-methyl-1-cyanoalkene fragments in five-membered ring A. Regioselective reduction of 1-cyano-19β,28-epoxy-2-nor-18αH-olean-1(3)-ene by DIBAL-H synthesized 2-aminomethyl-19β,28-epoxy-2-nor-18αH-olean-1(3)-ene. The synthesized triterpene… read more here.
Keywords: transformation cyano; triterpene alkenenitriles; cyano group; regioselective transformation ... See more keywords