Further studies on the application of vinylogous amides and β-halovinylaldehydes to the regiospecific synthesis of unsymmetrical, polyfunctionalized 2,3,4- and 1,2,3,4- substituted pyrroles.
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DOI: 10.1016/j.tet.2018.04.017
Abstract: Highly functionalized pyrroles with appropriate regiochemical functionality represent an important class of marine natural products and potential drug candidates. We describe herein a detailed study of the reaction of α-aminoacid esters with vinylogous amides and… read more here.
Keywords: amides halovinylaldehydes; regiospecific synthesis; substituted pyrroles; vinylogous amides ... See more keywords
Regiospecific Synthesis of Three Quercetin O-β-Glucosides of N-Acetylglucosamine
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Chemical Research"
DOI: 10.3184/174751918x15232706115112
Abstract: The regiospecific synthesis of three quercetin O-β-glucosides of N-acetylglucosamine has been achieved in good yield. Selective di-and tri-O-benzylation of quercetin followed by O-glycosylation with 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl chloride under phase-transfer catalysis conditions yielded, after deacetylation and debenzylation,… read more here.
Keywords: regiospecific synthesis; glucosides acetylglucosamine; three quercetin; quercetin glucosides ... See more keywords