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   Articles with "registration clinicaltrials" as a keyword



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A patent review of BRAF inhibitors: 2013-2018

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recommendations! Published in 2019 at "Expert Opinion on Therapeutic Patents"

DOI: 10.1080/13543776.2019.1640680

Abstract: ABSTRACT Introduction: As a key element in arguably the most important pathway MAPK signaling, the BRAF kinase gives rise to severe diseases including cancers when pathologically activated. Extensive research on BRAFi (BRAF inhibitor) has been… read more here.

Keywords: brafi; trial registration; registration clinicaltrials; braf ... See more keywords
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The NK1 receptor antagonist serlopitant for treatment of chronic pruritus

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recommendations! Published in 2019 at "Expert Opinion on Investigational Drugs"

DOI: 10.1080/13543784.2019.1638910

Abstract: ABSTRACT Introduction: Pruritus is a common symptom associated with several potential underlying causes, including both dermatologic and systemic diseases; it can also occur without an identifiable cause. Current treatment options are limited and most patients… read more here.

Keywords: trial registration; clinicaltrials gov; gov identifier; registration clinicaltrials ... See more keywords
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Investigational drugs in early-stage clinical trials for autism spectrum disorder

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recommendations! Published in 2019 at "Expert Opinion on Investigational Drugs"

DOI: 10.1080/13543784.2019.1649656

Abstract: ABSTRACT Introduction: Pharmacologic interventions in Autism Spectrum Disorder (ASD) have historically focused on symptom-based approaches. However, a treatment for the core social deficits has remained unidentified. While a definitive theory for the cause of ASD… read more here.

Keywords: trial registration; clinicaltrials gov; gov identifier; registration clinicaltrials ... See more keywords
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Current and emerging biologics for the treatment of hereditary angioedema

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recommendations! Published in 2019 at "Expert Opinion on Biological Therapy"

DOI: 10.1080/14712598.2019.1595581

Abstract: ABSTRACT Introduction: Hereditary angioedema due to C1-INH deficiency (C1-INH-HAE) is a rare disease with unpredictable, self-limiting and localized swelling episodes involving the cutaneous and subcutaneous tissues. In the last decade, the spectrum of the possibilities… read more here.

Keywords: trial registration; clinicaltrials gov; gov identifier; registration clinicaltrials ... See more keywords
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Monoclonal antibodies: new chance in the management of B-cell acute lymphoblastic leukemia

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recommendations! Published in 2022 at "Hematology"

DOI: 10.1080/16078454.2022.2074704

Abstract: ABSTRACT Objectives This review aims to see the progress of several clinically-used monoclonal antibodies in treating ALL patients and how they improved patients' outcomes. Methods We searched Web of Science, Elsevier and PubMed for relevant… read more here.

Keywords: gov identifier; clinicaltrials gov; registration clinicaltrials; trial registration ... See more keywords
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Evaluating the safety profile of focused ultrasound and microbubble-mediated treatments to increase blood-brain barrier permeability

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recommendations! Published in 2019 at "Expert Opinion on Drug Delivery"

DOI: 10.1080/17425247.2019.1567490

Abstract: ABSTRACT Introduction: Treatment of several diseases of the brain are complicated by the presence of the skull and the blood-brain barrier (BBB). Focused ultrasound (FUS) and microbubble (MB)-mediated BBB treatment is a minimally invasive method… read more here.

Keywords: trial registration; clinicaltrials gov; gov identifier; registration clinicaltrials ... See more keywords