Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression
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DOI: 10.1016/j.celrep.2020.108574
Abstract: SUMMARY The zinc finger transcription factor SALL4 is highly expressed in embryonic stem cells, downregulated in most adult tissues, but reactivated in many aggressive cancers. This unique expression pattern makes SALL4 an attractive therapeutic target.… read more here.
Keywords: zinc finger; regulate gene; expression; gene expression ... See more keywords
Conserved G-Quadruplex Motifs Regulate Gene Expression in Neisseria meningitidis.
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DOI: 10.1021/acsinfecdis.1c00383
Abstract: The noncanonical structures, G-quadruplexes (GQs), formed in the guanine-rich region of nucleic acids regulate various biological and molecular functions in prokaryotes and eukaryotes. Neisseria meningitidis is a commensal residing in a human's upper respiratory tract… read more here.
Keywords: neisseria meningitidis; conserved quadruplex; gene expression; regulate gene ... See more keywords
Corrigendum: Adipose-derived circulating miRNAs regulate gene expression in other tissues.
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature22319
Abstract: Nature 542, 450–455 (2017); doi:10.1038/nature21365 In this Article, in Fig. 4f–h, the x-axis labels ‘WT + exoKO’ and ‘ADicerKO + exoKO’ were inadvertently reversed, and in Fig. 5c, f, the y-axis labels should have been… read more here.
Keywords: corrigendum adipose; circulating mirnas; regulate gene; derived circulating ... See more keywords
FIRE: functional inference of genetic variants that regulate gene expression
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx534
Abstract: Motivation: Interpreting genetic variation in noncoding regions of the genome is an important challenge for personal genome analysis. One mechanism by which noncoding single nucleotide variants (SNVs) influence downstream phenotypes is through the regulation of… read more here.
Keywords: gene expression; regulate gene; expression; eqtl snvs ... See more keywords
Zyxin: a mechanotransductor to regulate gene expression.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201901_16790
Abstract: OBJECTIVE Cells answer to biochemical, electrical and mechanical signals in the environment, which regulate their behavior. Mechanical signals can propagate through mechanically stiff structures like focal adhesions (FAs). Zyxin, a LIM domain protein, is localized… read more here.
Keywords: mechanotransductor regulate; gene expression; regulate gene; zyxin ... See more keywords