Hedgehog-interacting protein acts in the habenula to regulate nicotine intake
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2209870119
Abstract: Significance Allelic variation in HHIP confers risk of smoking-related lung disease. We show that HHIP is expressed in the medial habenula, where it regulates the motivational properties of nicotine. These findings have relevance for understanding… read more here.
Keywords: habenula regulate; protein acts; interacting protein; acts habenula ... See more keywords
Ovarian Hormones Regulate Nicotine Consumption and Accumbens Glutamatergic Plasticity in Female Rats
Sign Up to like & getrecommendations! Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0286-21.2022
Abstract: Abstract Women report greater cigarette cravings during the menstrual cycle phase with higher circulating levels of 17β-estradiol (E2), which is metabolized to estrone (E1). Both E2 and E1 bind to estrogen receptors (ERs), which have… read more here.
Keywords: consumption; female rats; nicotine consumption; glutamatergic plasticity ... See more keywords