Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway.
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DOI: 10.18632/oncotarget.16875
Abstract: Alpha-ketoglutarate (AKG) is a critical nutritional factor in the maintenance of intestinal homeostasis. However, the relative mechanism of AKG has not been well understood. It was recently shown that the interaction between nuclear factor kappa… read more here.
Keywords: alpha ketoglutarate; regulated detoxification; pxr regulated; pathway ... See more keywords