Arabidopsis thaliana cold-regulated 47 gene 5'-untranslated region enables stable high-level expression of transgenes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2017.08.007
Abstract: Transgene expression is regulated through several steps, this study focuses on the mRNA translation step. The expression level of transgenes can be increased by 5'-untranslated region (5'UTR) sequences in certain genes which act as translational… read more here.
Keywords: cold regulated; level; expression; regulated gene ... See more keywords
Down-regulation of taurine-up-regulated gene 1 attenuates inflammation by sponging miR-9-5p via targeting NF-κB1/p50 in multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116731
Abstract: AIMS Multiple sclerosis (MS) is an inflammatory disease of the central nervous system characterized by widespread inflammation. LncRNA taurine-up-regulated gene 1 (TUG1) has been reported to be involved in multiple biological processes and human diseases.… read more here.
Keywords: taurine regulated; tug1; inflammation sponging; mir ... See more keywords
A Dexamethasone-regulated Gene Signature Is Prognostic for Poor Survival in Glioblastoma Patients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurosurgical Anesthesiology"
DOI: 10.1097/ana.0000000000000368
Abstract: Background: Dexamethasone is reported to induce both tumor-suppressive and tumor-promoting effects. The purpose of this study was to identify the genomic impact of dexamethasone in glioblastoma stem cell (GSC) lines and its prognostic value; furthermore,… read more here.
Keywords: dexamethasone regulated; gene signature; glioblastoma; regulated gene ... See more keywords
Acid‐regulated gene expression of Helicobacter pylori: Insight into acid protection and gastric colonization
Sign Up to like & getrecommendations! Published in 2018 at "Helicobacter"
DOI: 10.1111/hel.12490
Abstract: The pathogen Helicobacter pylori encounters many stressors as it transits to and infects the gastric epithelium. Gastric acidity is the predominate stressor encountered by the bacterium during initial infection and establishment of persistent infection. H.… read more here.
Keywords: helicobacter; regulated gene; helicobacter pylori; acid regulated ... See more keywords
Corrigendum to “Expression of Intratumoral IGF-II Is Regulated by the Gene Imprinting Status in Triple Negative Breast Cancer from Vietnamese Patients”
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Endocrinology"
DOI: 10.1155/2018/8434297
Abstract: [This corrects the article DOI: 10.1155/2015/401851.]. read more here.
Keywords: igf regulated; corrigendum expression; gene imprinting; expression intratumoral ... See more keywords
Computational study of parameter sensitivity in DevR regulated gene expression
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0228967
Abstract: The DevRS two-component system plays a pivotal role in signal transmission and downstream gene regulation in Mycobacterium tuberculosis. Under the hypoxic condition, phosphorylated DevR interacts with multiple binding sites at the promoter region of the… read more here.
Keywords: devr regulated; gene expression; sensitivity; regulated gene ... See more keywords
Light-regulated gene expression in Bacteria: Fundamentals, advances, and perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1029403
Abstract: Numerous photoreceptors and genetic circuits emerged over the past two decades and now enable the light-dependent i.e., optogenetic, regulation of gene expression in bacteria. Prompted by light cues in the near-ultraviolet to near-infrared region of… read more here.
Keywords: light regulated; regulated gene; expression bacteria; expression ... See more keywords
Characterization of glycosylation regulator-mediated glycosylation modification patterns and tumor microenvironment infiltration in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1001901
Abstract: Background: Previous studies have shown that glycosylation of proteins ofen plays an important role in HCC. However, the potential mechanism of glycosylation in HCC has not been described systematically. Methods: We comprehensively evaluated the glycosylation… read more here.
Keywords: glycosylation score; regulated gene; hcc; glycosylation ... See more keywords
Single cell analysis of docosahexaenoic acid suppression of sequential LPS-induced proinflammatory and interferon-regulated gene expression in the macrophage
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.993614
Abstract: Preclinical and clinical studies suggest that consumption of long chain omega-3 polyunsaturated fatty acids (PUFAs) reduces severity of chronic inflammatory and autoimmune diseases. While these ameliorative effects are conventionally associated with downregulated expression of proinflammatory… read more here.
Keywords: lps induced; regulated gene; gene expression; expression ... See more keywords
Estrogen Receptor-Regulated Gene Signatures in Invasive Breast Cancer Cells and Aggressive Breast Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14122848
Abstract: Simple Summary Metastatic breast cancer remains a major clinical problem, contributing to significant patient mortality, which is partly due to a lack of understanding around the early changes within the primary tumor. Tumors frequently become… read more here.
Keywords: regulated gene; breast cancer; breast; gene signatures ... See more keywords
Chemotherapy-induced hypomethylation of N-myc downstream-regulated gene 4 in the bone marrow of patients with acute myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2017.5839
Abstract: N-myc downstream-regulated gene 4 (NDRG4) has previously been investigated as a possible tumor suppressor. Hypermethylation of tumor suppressor genes contributes to the occurrence and development of certain types of cancer, including acute myeloid leukemia (AML).… read more here.
Keywords: chemotherapy; methylation; downstream regulated; myc downstream ... See more keywords