HMGB1 was negatively regulated by HSF1 and mediated the TLR4/MyD88/NF-κB signal pathway in asthma.
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DOI: 10.1016/j.lfs.2019.117120
Abstract: AIMS The present study explored the function and regulatory mechanism of High mobility group box 1 (HMGB1) in asthma. MAIN METHODS OVA (ovalbumin)-induced asthmatic mice model and LPS-treated cellular model were established in this study.… read more here.
Keywords: hmgb1; negatively regulated; signal pathway; regulated hsf1 ... See more keywords