Regulated proteolysis of p62/SQSTM1 enables differential control of autophagy and nutrient sensing
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DOI: 10.1126/scisignal.aat6903
Abstract: A p62 fragment generated by caspase-8 regulates responses to nutrient availability, rather than autophagy. Cleaving a different function for p62 The scaffold protein p62 has a critical role in autophagy, the regulated degradation of proteins… read more here.
Keywords: caspase; p62trm; regulated proteolysis; p62 ... See more keywords
Metabolic adaption through regulated proteolysis
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DOI: 10.1126/scisignal.aba2257
Abstract: Induced mitochondrial protein turnover enables cells to metabolically adapt to oxygen and nutrient deprivation. Induced mitochondrial protein turnover enables cells to metabolically adapt to oxygen and nutrient deprivation. read more here.
Keywords: metabolic adaption; regulated proteolysis; adaption regulated;
Role of Regulated Proteolysis in the Communication of Bacteria With the Environment
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DOI: 10.3389/fmolb.2020.586497
Abstract: For bacteria to flourish in different niches, they need to sense signals from the environment and translate these into appropriate responses. Most bacterial signal transduction systems involve proteins that trigger the required response through the… read more here.
Keywords: proteolysis; response; regulated proteolysis; process ... See more keywords