CD59-Regulated Ras Compartmentalization Orchestrates Antitumor T-cell Immunity
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DOI: 10.1158/2326-6066.cir-21-1072
Abstract: The subcellular compartmentalization of Ras is regulated by interacting with intracellular CD59. CD59 deficiency results in reduced trafficking of Ras to the plasma membrane in T cells, thus inducing increased T-cell signal transduction and antitumor… read more here.
Keywords: ras compartmentalization; regulated ras; compartmentalization; cd59 ... See more keywords