LI1035, a putative effector secreted by Lawsonia intracellularis, targets the MAPK pathway and regulates actin organizationin yeast and mammalian cells.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2019.06.009
Abstract: Lawsonia intracellularis is an obligate intracellular Gram-negative bacterium that has been identified as the etiological agent of the contagious disease proliferative enteropathy (PE) in a wide range of animals, mainly pigs. The genome sequence of… read more here.
Keywords: yeast mammalian; mapk pathway; mammalian cells; lawsonia intracellularis ... See more keywords
Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-35204-x
Abstract: Calpain-10 (CAPN10) is the calpain family protease identified as the first candidate susceptibility gene for type 2 diabetes mellitus (T2DM). However, the detailed molecular mechanism has not yet been elucidated. Here we report that CAPN10… read more here.
Keywords: associated protein; microtubule associated; calpain regulates; family ... See more keywords
STK16 regulates actin dynamics to control Golgi organization and cell cycle
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DOI: 10.1038/srep44607
Abstract: STK16 is a ubiquitously expressed, myristoylated, and palmitoylated serine/threonine protein kinase with underexplored functions. Recently, it was shown to be involved in cell division but the mechanism remains unclear. Here we found that human STK16… read more here.
Keywords: cell cycle; stk16; regulates actin; cell ... See more keywords