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Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27997
Abstract: Osteoarthritis (OA) is a complex chronic degenerative joint disease involving oxidative stress, inflammation, and apoptosis of chondrocytes. As decoys of micro RNAs, long non‐coding RNAs (lncRNAs) play important roles in various biological processes. This study…
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Keywords:
apoptosis chondrocytes;
regulates cell;
lncrna cir;
apoptosis ... See more keywords
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Published in 2017 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22490
Abstract: The tumor suppressor p27, which is a member of the Cip/Kip family of Cyclin‐dependent kinase inhibitory proteins (CKIs), controls anti‐proliferative events. The post‐translational addition of O‐GlcNAc to p27 occurs in HEK293T and HCC (hepatocellular carcinoma)…
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Keywords:
hepatocellular carcinoma;
cell proliferation;
regulates cell;
p27 ... See more keywords
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Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.007
Abstract: The protein arginine methyltransferase 6 (PRMT6) is a coregulator of gene expression by methylation of the histone H3 on arginine 2 (H3R2), H4R3 and H2AR3 [1,2]. PRMT6 is aberrantly expressed in various types of human…
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Keywords:
degradation;
prmt6;
regulates cell;
fbxo24 regulates ... See more keywords
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Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.06.014
Abstract: Pds5b (precocious dissociation of sisters 5B) is involved in both tumorigenesis and cancer progression; however, the functions and molecular mechanisms of Pds5b in pancreatic cancer (PC) are unknown. Several approaches were conducted to investigate the…
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Keywords:
regulates cell;
cell proliferation;
pds5b;
pancreatic cancer ... See more keywords
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Published in 2017 at "Leukemia"
DOI: 10.1038/leu.2017.89
Abstract: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematopoietic neoplasm resulting from the malignant transformation of T-cell progenitors, and comprises ~15% and 25% of pediatric and adult ALL cases, respectively. It is well-established that activating…
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Keywords:
dnmt3a regulates;
dnmt3a;
regulates cell;
development suppresses ... See more keywords
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Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29725-3
Abstract: TCR stimulation triggers Ca2+ signals that are critical for T cell function and immunity. Several pore-forming α and auxiliary β subunits of voltage-gated Ca2+ channels (VGCC) were reported in T cells, but their mechanism of…
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Keywords:
regulates cell;
gated ca2;
voltage gated;
cav regulates ... See more keywords
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Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29930-0
Abstract: Programmed death-1 (PD-1) and its ligand PD-L1 are checkpoint molecules which regulate immune responses. Little is known about their functions in T cell migration and there are contradictory data about their roles in regulatory T…
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Keywords:
regulates cell;
selectively regulates;
transendothelial migration;
signaling selectively ... See more keywords
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Published in 2018 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.12974
Abstract: The development of the placenta and its functions are sensitive to infection and stress, which can activate the hypothalamic‐pituitary‐adrenal axis. Adrenally produced glucocorticoids are the body's primary mediators of the inflammatory and stress response. Although…
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Keywords:
regulates cell;
glucocorticoid signaling;
invasion migration;
signaling regulates ... See more keywords
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Published in 2017 at "Molecular Microbiology"
DOI: 10.1111/mmi.13839
Abstract: When the cell envelope integrity is compromised, bacteria trigger signaling cascades resulting in the production of proteins that counteract these extracytoplasmic stresses. Here, we show that the two‐component system EsrSR regulates a cell envelope stress…
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Keywords:
component system;
cell envelope;
system;
regulates cell ... See more keywords
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Published in 2023 at "Science"
DOI: 10.1126/science.adg9605
Abstract: Description Structural analysis reveals how the decision to induce apoptotic cell death is regulated Cells are bombarded with signals about their environment, which they integrate to decide an appropriate response. Danger signals elicit the most…
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Keywords:
cell death;
massive machine;
machine regulates;
death ... See more keywords
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Published in 2020 at "mBio"
DOI: 10.1128/mbio.02815-19
Abstract: Control of mRNA localization, stability, turnover, and translation by RNA-binding proteins (RBPs) influences essential processes in all eukaryotes, including signaling by mitogen-activated protein kinase (MAPK) pathways. We describe that in the fission yeast Schizosaccharomyces pombe…
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Keywords:
rnc1;
kinase;
growth;
regulates cell ... See more keywords