E3 Ubiquitin Ligase Constitutive Photomorphogenic 1 Regulates Differentiation and Inflammation via MAPK Signaling Pathway in Rabbit Articular Chondrocytes.
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DOI: 10.1089/dna.2022.0664
Abstract: Constitutive photomorphogenic 1 (COP1), is an E3 ubiquitin ligase that plays a role in the regulation of various cellular processes including cell growth, differentiation, and survival in mammals. In certain conditions such as overexpression or… read more here.
Keywords: differentiation inflammation; regulates differentiation; ubiquitin ligase; articular chondrocytes ... See more keywords
ATM Regulates Differentiation of Myofibroblastic Cancer-Associated Fibroblasts and Can Be Targeted to Overcome Immunotherapy Resistance
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DOI: 10.1158/0008-5472.can-22-0435
Abstract: ATM signaling supports the differentiation of myoCAFs to suppress T-cell infiltration and antitumor immunity, supporting the potential clinical use of ATM inhibitors in combination with checkpoint inhibition in myoCAF-rich, immune-cold tumors. read more here.
Keywords: differentiation myofibroblastic; regulates differentiation; atm regulates; atm ... See more keywords