PD-1 Regulates GABAergic Neurotransmission and GABA-Mediated Analgesia and Anesthesia
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DOI: 10.1016/j.isci.2020.101570
Abstract: Summary The immune checkpoint inhibitor programmed cell death protein 1 (PD-1) plays a critical role in immune regulation. Recent studies have demonstrated functional PD-1 expression in peripheral sensory neurons, which contributes to neuronal excitability, pain,… read more here.
Keywords: analgesia anesthesia; regulates gabaergic; mediated analgesia; gaba ... See more keywords
The small GTPase ARF6 regulates GABAergic synapse development
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DOI: 10.1186/s13041-019-0543-3
Abstract: ADP ribosylation factors (ARFs) are a family of small GTPases composed of six members (ARF1–6) that control various cellular functions, including membrane trafficking and actin cytoskeletal rearrangement, in eukaryotic cells. Among them, ARF1 and ARF6… read more here.
Keywords: arf6; regulates gabaergic; arf6 regulates; small gtpase ... See more keywords