Nitroxide Tempol down-regulates kinase activities associated with NADPH oxidase function in phagocytic cells and potentially decreases their fungicidal response.
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DOI: 10.1016/j.cbi.2017.11.016
Abstract: AIMS The identification of novel targets to control inflammation in humans is probably the primary challenge that impairs the development of new anti-inflammatory drugs. Therefore, the modulation of intracellular signaling pathways in phagocytes may be… read more here.
Keywords: tempol regulates; response; kinase activities; regulates kinase ... See more keywords