IL-15RA regulates IL-15 localization and protein expression in skeletal muscle cells.
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DOI: 10.1113/ep090205
Abstract: NEW FINDINGS What is the central question of this study? How are the dynamics of IL-15 and its receptors altered during the differentiation of myoblasts into myotubes, and how is IL-15 regulated? What is the… read more here.
Keywords: expression; differentiation; 15ra regulates; muscle ... See more keywords
Acid sphingomyelinase regulates the localization and trafficking of palmitoylated proteins
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DOI: 10.1242/bio.040311
Abstract: ABSTRACT In human, loss of acid sphingomyelinase (ASM/SMPD1) causes Niemann–Pick disease, type A. ASM hydrolyzes sphingomyelins to produce ceramides but protein targets of ASM remain largely unclear. Our mass spectrometry-based proteomic analyses have identified >100… read more here.
Keywords: plasma membrane; acid sphingomyelinase; palmitoylated proteins; regulates localization ... See more keywords