ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin.
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DOI: 10.1016/j.celrep.2020.107993
Abstract: β-Hemoglobinopathies can trigger rapid production of red blood cells in a process known as stress erythropoiesis. Cellular stress prompts differentiating erythroid precursors to express high levels of fetal γ-globin. However, the mechanisms underlying γ-globin production… read more here.
Keywords: globin; response; atf4; stress ... See more keywords