TFG regulates secretory and endosomal sorting pathways in neurons to promote their activity and maintenance
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DOI: 10.1073/pnas.2210649119
Abstract: Significance Pathological mutations in TFG have been implicated in a variety of neurodegenerative diseases, including early-onset forms of hereditary spastic paraplegia (HSP). In this work, we demonstrate that the TFG p.R106C mutation, which has been… read more here.
Keywords: secretory endosomal; maintenance; regulates secretory; tfg ... See more keywords