Low adenylate kinase 5 expression is predictive of poor prognosis and promotes tumour growth by regulating the cell‐cycle pathway
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13680
Abstract: Colon adenocarcinoma (COAD) is one of the most common malignant tumours of the digestive system. Specific molecular markers play an important role in COAD diagnosis and therapy. Adenylate kinase 5 (AK5) is an enzyme that… read more here.
Keywords: ak5 expression; regulating cell; coad; cell cycle ... See more keywords
Research Progress on the Anticancer Molecular Mechanism of Targets Regulating Cell Autophagy.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacology"
DOI: 10.1159/000529279
Abstract: BACKGROUND Autophagy is a lysosome-mediated catabolic process that maintains cell homeostasis and survival. It occurs not only in normal cells such as cardiac muscle cells, neurons, and pancreatic acinar cells but also in various benign… read more here.
Keywords: progress anticancer; cell; anticancer molecular; regulating cell ... See more keywords
miRNAs in the Beta Cell—Friends or Foes?
Sign Up to like & getrecommendations! Published in 2023 at "Endocrinology"
DOI: 10.1210/endocr/bqad040
Abstract: Abstract Type 2 diabetes (T2D) develops due to insulin resistance and an inability of the pancreatic β-cells to increase secretion of insulin and reduce elevated blood glucose levels. Diminished β-cell function and mass have been… read more here.
Keywords: cell; regulating cell; cell function; secretion ... See more keywords
SAD-A Promotes Pancreatic ß-Cell Proliferation by Regulating ß-Cell Cycle as a Downstream Target of mTORC1 Signaling
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes"
DOI: 10.2337/db18-53-or
Abstract: Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance and β-cell dysfunction, which leads to the depletion of β-cell mass. Understanding the molecular mechanisms driving islet β-cell dysfunction is paramount for developing therapies to… read more here.
Keywords: regulating cell; cell proliferation; target; cell cycle ... See more keywords