Bioactive polypeptide improves neuroinflammation by regulating microglia polarization
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17059
Abstract: Tolllike receptor (TLR) was first discovered during a research of embryonic development in Drosophila.1 As a class of natural immune receptors, TLRs can identify pathogenassociated molecular patterns (PAMP)2 to initiate relevant signalling pathways, which play… read more here.
Keywords: regulating microglia; bioactive polypeptide; microglia polarization; polypeptide improves ... See more keywords
Echinacoside exerts antidepressant-like effects through enhancing BDNF-CREB pathway and inhibiting neuroinflammation via regulating microglia M1/M2 polarization and JAK1/STAT3 pathway
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.993483
Abstract: The present study was performed to investigate the antidepressant effect of echinacoside (ECH) using chronic unpredictable mild stress (CUMS) induced depression mice and lipopolysaccharide (LPS)-stimulated N9 microglial cells. CUMS treatment was performed on C57BL/6 mice… read more here.
Keywords: microglia polarization; regulating microglia; bdnf; pathway ... See more keywords