The Key Roles of GSK-3β in Regulating Mitochondrial Activity
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000485580
Abstract: Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, has been reported to show essential roles in molecular pathophysiology of many diseases. Mitochondrion is a dynamic organelle for producing cellular energy and determining cell fates. Stress-induced… read more here.
Keywords: key roles; gsk regulating; roles gsk; mitochondrial activity ... See more keywords
Drosophila Caliban preserves intestinal homeostasis and lifespan through regulating mitochondrial dynamics and redox state in enterocytes
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009140
Abstract: Precise regulation of stem cell activity is crucial for tissue homeostasis. In Drosophila, intestinal stem cells (ISCs) maintain the midgut epithelium and respond to oxidative challenges. However, the connection between intestinal homeostasis and redox signaling… read more here.
Keywords: homeostasis; clbn; drosophila caliban; intestinal homeostasis ... See more keywords
Research progress on the pharmacological effects of berberine targeting mitochondria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.982145
Abstract: Berberine is a natural active ingredient extracted from the rhizome of Rhizoma Coptidis, which interacts with multiple intracellular targets and exhibits a wide range of pharmacological activities. Previous studies have preliminarily confirmed that the regulation… read more here.
Keywords: regulating mitochondrial; effects berberine; progress pharmacological; mitochondrial activity ... See more keywords
The multifaceted roles of natural products in mitochondrial dysfunction
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1093038
Abstract: Mitochondria are the primary source of energy production in cells, supporting the metabolic demand of tissue. The dysfunctional mitochondria are implicated in various diseases ranging from neurodegeneration to cancer. Therefore, regulating dysfunctional mitochondria offers a… read more here.
Keywords: products mitochondrial; regulating mitochondrial; natural products; mitochondrial dysfunction ... See more keywords
Diet Restriction Impact on High-Fat-Diet-Induced Obesity by Regulating Mitochondrial Cardiolipin Biosynthesis and Remodeling
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28114522
Abstract: Diet restriction (DR) ameliorates obesity by regulating mitochondrial function. Cardiolipin (CL), a mitochondrial phospholipid, is closely associated with mitochondrial function. This study aimed to evaluate the anti-obesity effects of graded levels of DR based on… read more here.
Keywords: regulating mitochondrial; diet restriction; biosynthesis remodeling; obesity regulating ... See more keywords
Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function
Sign Up to like & getrecommendations! Published in 2020 at "BMB Reports"
DOI: 10.5483/bmbrep.2020.53.12.168
Abstract: The N-myc downstream regulated gene (NDRG) family members are dysregulated in several tumors. Functionally, NDRGs play an important role in the malignant progression of cancer cells. However, little is known about the potential implications of… read more here.
Keywords: pdac; silencing ndrg4; mitochondrial function; regulating mitochondrial ... See more keywords