Amyloid-beta (1-42) lesion of CA1 rat dorsal hippocampus reduces contextual fear memory and increases expression of microglial genes regulating neuroinflammation
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.112795
Abstract: Emerging evidence indicates that the pathogenesis of Alzheimer's disease (AD) is not confined to neuronal disruptions but robustly communicates with the brain's immune system. Genome-wide analysis suggests that several genes, which increase the risk for… read more here.
Keywords: memory; genes regulating; neuroinflammation; fear memory ... See more keywords
Possible Epigenetic Role of Vitexin in Regulating Neuroinflammation in Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Immunology Research"
DOI: 10.1155/2020/9469210
Abstract: Alzheimer's disease (AD) has been clinically characterized by a progressive degeneration of neurons which resulted in a gradual and irreversible cognitive impairment. The accumulation of Aβ and τ proteins in the brain contribute to the… read more here.
Keywords: vitexin; alzheimer disease; disease; regulating neuroinflammation ... See more keywords