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Regulating Polyamine Metabolism by miRNAs in Diabetic Cardiomyopathy

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0 Published in 2021 at "Current Diabetes Reports"

DOI: 10.1007/s11892-021-01429-w

Abstract: Insulin is at the heart of diabetes mellitus (DM). DM alters cardiac metabolism causing cardiomyopathy, ultimately leading to heart failure. Polyamines, organic compounds synthesized by cardiomyocytes, have an insulin-like activity and effect on glucose metabolism,… read more here.

Keywords: diabetic cardiomyopathy; heart; polyamine biosynthesis; metabolism ... See more keywords