De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abo7112
Abstract: Stress granules (SGs) are cytoplasmic assemblies in response to a variety of stressors. We report a new neurodevelopmental disorder (NDD) with common features of language problems, intellectual disability, and behavioral issues caused by de novo… read more here.
Keywords: genes regulating; stress; stress granule; novo variants ... See more keywords
The Role of Ubiquitin in Regulating Stress Granule Dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.910759
Abstract: Stress granules (SGs) are dynamic, reversible biomolecular condensates, which assemble in the cytoplasm of eukaryotic cells under various stress conditions. Formation of SGs typically occurs upon stress-induced translational arrest and polysome disassembly. The increase in… read more here.
Keywords: stress; ubiquitin regulating; role ubiquitin; role ... See more keywords