Articles with "regulation" as a keyword



Which Features of Dietary Supplement Industry, Product Trends, and Regulation Deserve Physicians' Attention?

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Published in 2022 at "AMA journal of ethics"

DOI: 10.1001/amajethics.2022.410

Abstract: Patients expect that dietary supplements they purchase-and physicians expect that dietary supplements they recommend-are safe, accurately labeled, quality products. Since many dietary supplements, especially vitamins and minerals, are key parts of evidence-based interventions for patients… read more here.

Keywords: supplement; features dietary; supplement industry; dietary supplement ... See more keywords

The translational regulation of maternal mRNAs in time and space

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Published in 2018 at "Febs Letters"

DOI: 10.1002/1873-3468.13183

Abstract: Since their discovery, the study of maternal mRNAs has led to the identification of mechanisms underlying their spatiotemporal regulation within the context of oogenesis and early embryogenesis. Following synthesis in the oocyte, maternal mRNAs are… read more here.

Keywords: time; regulation maternal; maternal mrnas; translational regulation ... See more keywords

A twist in the ABC: regulation of ABC transporter trafficking and transport by FK506‐binding proteins

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Published in 2020 at "FEBS Letters"

DOI: 10.1002/1873-3468.13983

Abstract: Post‐transcriptional regulation of ATP‐binding cassette (ABC) proteins has been so far shown to encompass protein phosphorylation, maturation, and ubiquitination. Yet, recent accumulating evidence implicates FK506‐binding proteins (FKBPs), a type of peptidylprolyl cis–trans isomerase (PPIase) proteins,… read more here.

Keywords: binding proteins; abc transporter; abc; fk506 binding ... See more keywords

An update on post‐transcriptional regulation of retrotransposons

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Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14551

Abstract: Retrotransposons, including LINE‐1, Alu, SVA, and endogenous retroviruses, are one of the major constituents of human genomic repetitive sequences. Through the process of retrotransposition, some of them occasionally insert into new genomic locations by a… read more here.

Keywords: update post; rna; regulation; post transcriptional ... See more keywords

A rapid in vivo assay to study the regulation of gene expression

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Published in 2025 at "FEBS Letters"

DOI: 10.1002/1873-3468.70096

Abstract: Traditional in vivo studies of gene regulation often require labor‐intensive protocols and animal sacrifice. Here, we present a minimally invasive method—In Vivo Imaging of Subcutaneous Luminescence (IVISc‐L)—for analyzing gene regulation in live mice. The assay… read more here.

Keywords: rapid vivo; gene expression; study; gene ... See more keywords

The role of histone modifications in transcription regulation upon DNA damage.

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Published in 2025 at "FEBS letters"

DOI: 10.1002/1873-3468.70241

Abstract: Cells are constantly exposed to various sources of DNA damage, including radiation, chemicals, replicative stress and oxidative stress, that threaten genome stability. To ensure faithful DNA repair, transcription regulation needs to be tightly controlled. This… read more here.

Keywords: dna damage; repair; regulation; transcription ... See more keywords

Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1/RIPK1 signaling.

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Published in 2023 at "Molecular oncology"

DOI: 10.1002/1878-0261.13374

Abstract: Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity-dependent labeling (PDL) with biotin followed… read more here.

Keywords: abi1; role; ripk1; regulation ... See more keywords
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TSC2/Rheb signaling mediates ERK‐dependent regulation of mTORC1 activity in C2C12 myoblasts

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Published in 2017 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12195

Abstract: The enhanced rate of protein synthesis in skeletal muscle cells results in a net increase in total protein content that leads to skeletal muscle growth/hypertrophy. The mitogen‐activated protein kinase kinase (MEK)/extracellular signal‐regulated kinase (ERK)‐dependent regulation… read more here.

Keywords: c2c12 myoblasts; mtorc1; activation; erk dependent ... See more keywords

Nfat5 is involved in the hyperosmotic regulation of Tmem184b: a putative modulator of ibuprofen transport in renal MDCK I cells

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Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12630

Abstract: Nuclear factor of activated T cells 5 (NFAT5) is a transcription factor involved in the regulation of several genes involved in the response to extracellular hyperosmolality. Recently, the uptake of ibuprofen by an as yet… read more here.

Keywords: mdck cells; nfat5 involved; regulation; ibuprofen ... See more keywords

Mammaglobin 1 mediates progression of trastuzumab‐resistant breast cancer cells through regulation of cyclins and NF‐κB

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Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13468

Abstract: Overexpression of human epidermal growth factor receptor 2 (HER2) in various cancers is correlated with poor patient survival. Trastuzumab, a recombinant humanized monoclonal antibody against HER2, has been considered to be a first‐line therapy for… read more here.

Keywords: breast cancer; cancer cells; trastuzumab; regulation ... See more keywords

Possible role of human ribonuclease dicer in the regulation of R loops

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Published in 2025 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.70026

Abstract: R loops are three‐stranded nucleic acid structures that form naturally in cells under various conditions, mainly as intermediates during replication or as by‐products during transcription. R loops are involved in the regulation of many important… read more here.

Keywords: cancer; possible role; regulation loops; role human ... See more keywords