Feedback regulation by antagonistic epigenetic factors potentially maintains developmental homeostasis in Drosophila
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DOI: 10.1242/jcs.210179
Abstract: ABSTRACT Drosophila Polycomb group (PcG) repressors confer epigenetically heritable silencing on key regulatory genes through histone H3 trimethylation on lysine 27 (H3K27me3). How the silencing state withstands antagonistic activities from co-expressed trithorax group (trxG) activators… read more here.
Keywords: drosophila; h3k4 methylase; regulation antagonistic; feedback ... See more keywords